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Symmetry

Kelley Swanberg, Postdoc | LUNDGAARD LAB

Symmetry

The story

An intricate web of disparate experimental, signal acquisition, processing and analysis methods within in vivo proton magnetic resonance spectroscopy converges beautifully to depict the cortical metabolic similarities between two distinct species.

Research area

The glymphatic brain clearance system, in vivo functional and metabolic signatures of glymphatic health and disruption.

Impact

The utility of preclinical research rests in large part on the extent to which it can translate to human application.

Image description

Left: Cortical in vivo proton magnetic resonance (1H-MR) spectrum from a human adult at 7 Tesla. Right: Similar 1H-MRS data set from a mouse at 9.4 Tesla.

Credits

Art by K.M. Swanberg, Ph.D. Raw 7-T data from K. Markenroth-Bloch, Ph.D. Prelinical support from J. Jukkola, Ph.D.

Last updated: 5 Feb 2025 | lisa [dot] karlsson [at] med [dot] lu [dot] se