The Glow of HLS in Celestial Neurons
João Duarte, Associate Professor | DUARTE LAB
The story
This artwork celebrates the wonder and mystery of the microscopic world. A neuron stained for the enzyme hormone-sensitive lipase (HSL) glows like a celestial body in the vast expanse of the cell dish. The bright hues and intricate details highlight the presence of HSL throughout the neuron and in its in dendritic spines, where it interfaces lipid metabolism with the transmission of electrochemical signals to the neuron’s cell body.
Research area
Diabetes and Brain Function.
Impact
Neuronal hormone-sensitive lipase might be a way of improving synaptic function and memory performance in dementia.
Image description
Immunofluorescent staining of Hormone-sensitive lipase within a mouse cortical neuron in culture.
Credits
The Diabetes and Brain Function unit at Lund University.