In her thesis, Cecilia has explored the change in the lipidome and the consequences for brain function in type 2 diabetes (T2D). In metabolic diseases, such as obesity and T2D, the brain is impacted and variety of bioactive lipids and their signaling pathways can be altered. However, the implications are not well explored.
Cecilia focused in her thesis on one of the major lipases, hormone sensitive lipase (HSL) and the Sphingosine 1-phosphate (S1P) pathway, which can be putative targets for neuroprotection during T2D.
Read more about Cecilia Skoug in Lund University Research Portal