The already ongoing project entitled “Modulating key targets in pericytes: impact on tumor infiltration and immune evasion in glioblastoma” will investigate if and how modulation of previously selected targets in pericytes antagonize infiltrative growth and immune evasion of gliomas.
This project will provide novelty on key targets and their functional implications in the pathological context of glioblastoma that have the potential to limit tumor progression. Most of the work will be carried out in Gesine’s lab by PhD student Carolina Buizza and Gayatri Chitale as part of the of their PhD and master thesis.